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NRF2 is a major target of ARF in p53-independent tumor suppression
Although ARF can suppress tumor growth by activating p53 function, the mechanisms by which it suppresses tumor growth independently of p53 are not well understood. Here, we identified ARF as a key regulator of nuclear factor-E2-related factor 2 (NRF2) through complex purification. ARF inhibits the a...
Shranjeno v:
| izdano v: | Mol Cell |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5683418/ https://ncbi.nlm.nih.gov/pubmed/28985506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.09.009 |
| Oznake: |
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