MYCN contributes to the malignant characteristics of erythroleukemia through EZH2-mediated epigenetic repression of p21

MYC proto-oncogene family including c-myc and n-myc (MYCN) are critical for normal cell development and tumorigenesis. Overexpression of c-myc causes acute erythroleukemia in vivo. However, the role of MYCN in acute erythroleukemia remains poorly understood. In this study, we found that the patients...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Liu, Li, Xu, Feng, Chang, Chun-Kang, He, Qi, Wu, Ling-Yun, Zhang, Zheng, Li, Xiao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682688/
https://ncbi.nlm.nih.gov/pubmed/29022893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.526
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller