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STAT1β enhances STAT1 function by protecting STAT1α from degradation in esophageal squamous cell carcinoma

STAT1, which carries tumor suppressor functions in several models, consists of two isoforms, namely STAT1α and STAT1β. The biological function and significance of STAT1β has never been examined in human cancer. We examined STAT1β function in esophageal squamous cell carcinoma (ESCC) by transfecting...

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Publicado en:Cell Death Dis
Autores principales: Zhang, Ying, Chen, Yelong, Yun, Hailong, Liu, Zhaoyong, Su, Min, Lai, Raymond
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682650/
https://ncbi.nlm.nih.gov/pubmed/28981100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.481
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