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STAT1β enhances STAT1 function by protecting STAT1α from degradation in esophageal squamous cell carcinoma

STAT1, which carries tumor suppressor functions in several models, consists of two isoforms, namely STAT1α and STAT1β. The biological function and significance of STAT1β has never been examined in human cancer. We examined STAT1β function in esophageal squamous cell carcinoma (ESCC) by transfecting...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Ying, Chen, Yelong, Yun, Hailong, Liu, Zhaoyong, Su, Min, Lai, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682650/
https://ncbi.nlm.nih.gov/pubmed/28981100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.481
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