The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding

Vaccinia virus (VACV), the prototype member of the Poxviridae, replicates in the cytoplasm of an infected cell. The catalytic subunit of the DNA polymerase E9 binds the heterodimeric processivity factor A20/D4 to form the functional polymerase holoenzyme. Here we present the crystal structure of ful...

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Publicado no:Nat Commun
Main Authors: Tarbouriech, Nicolas, Ducournau, Corinne, Hutin, Stephanie, Mas, Philippe J., Man, Petr, Forest, Eric, Hart, Darren J., Peyrefitte, Christophe N., Burmeister, Wim P., Iseni, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682278/
https://ncbi.nlm.nih.gov/pubmed/29129932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01542-z
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