The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding

Vaccinia virus (VACV), the prototype member of the Poxviridae, replicates in the cytoplasm of an infected cell. The catalytic subunit of the DNA polymerase E9 binds the heterodimeric processivity factor A20/D4 to form the functional polymerase holoenzyme. Here we present the crystal structure of ful...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Tarbouriech, Nicolas, Ducournau, Corinne, Hutin, Stephanie, Mas, Philippe J., Man, Petr, Forest, Eric, Hart, Darren J., Peyrefitte, Christophe N., Burmeister, Wim P., Iseni, Frédéric
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682278/
https://ncbi.nlm.nih.gov/pubmed/29129932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01542-z
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