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Synthesis and anticancer activity of new quinazoline derivatives

In this study, a new series of quinazoline derivatives (3–26) was synthesized and characterized via physicochemical and spectral means. Treatment of 2-amino-5-methylbenzoic acid with butyl isothiocyanate resulted in the new 2-thioxoquinazolin-4-one (3). Alkylation and hydrazinolysis of the inherent...

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Detalles Bibliográficos
Publicado en:Saudi Pharm J
Main Authors: Abuelizz, Hatem A., Marzouk, Mohamed, Ghabbour, Hazem, Al-Salahi, Rashad
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681317/
https://ncbi.nlm.nih.gov/pubmed/29158714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2017.04.022
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