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A quality by design approach for the development of lyophilized liposomes with simvastatin

Lyophilization is used to ensure an increased shelf-life of liposomes, by preserving them in dry state, more stable than the aqueous dispersions. When stored as aqueous systems, the encapsulated drugs are released and the liposomes might aggregate or fuse. The aim of this study was to develop and op...

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Detalhes bibliográficos
Publicado no:Saudi Pharm J
Main Authors: Porfire, Alina, Muntean, Dana Maria, Rus, Lucia, Sylvester, Bianca, Tomuţă, Ioan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681309/
https://ncbi.nlm.nih.gov/pubmed/29158704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2017.01.007
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