Liposomal simvastatin sensitizes C26 murine colon carcinoma to the antitumor effects of liposomal 5‐fluorouracil in vivo

5‐Fluorouracil‐based therapy remains the main approach in colorectal cancer, even though there are still some drawbacks, such as chemoresistance. In this study we combined 5‐fluorouracil encapsulated in long‐circulating liposomes with simvastatin, also encapsulated in long‐circulating liposomes, tha...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Luput, Lavinia, Sesarman, Alina, Porfire, Alina, Achim, Marcela, Muntean, Dana, Casian, Tibor, Patras, Laura, Rauca, Valentin Florian, Drotar, Denise Minerva, Stejerean, Ioana, Tomuta, Ioan, Vlase, Laurian, Dragos, Nicolae, Toma, Vlad Alexandru, Licarete, Emilia, Banciu, Manuela
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156830/
https://ncbi.nlm.nih.gov/pubmed/31960547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14312
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