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A quality by design approach for the development of lyophilized liposomes with simvastatin

Lyophilization is used to ensure an increased shelf-life of liposomes, by preserving them in dry state, more stable than the aqueous dispersions. When stored as aqueous systems, the encapsulated drugs are released and the liposomes might aggregate or fuse. The aim of this study was to develop and op...

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書目詳細資料
發表在:Saudi Pharm J
Main Authors: Porfire, Alina, Muntean, Dana Maria, Rus, Lucia, Sylvester, Bianca, Tomuţă, Ioan
格式: Artigo
語言:Inglês
出版: Elsevier 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681309/
https://ncbi.nlm.nih.gov/pubmed/29158704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2017.01.007
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