The non-invasive serum biomarker soluble Axl accurately detects advanced liver fibrosis and cirrhosis

Soluble Axl (sAxl) was recently shown to be strongly released into the blood during liver fibrogenesis and hepatocellular carcinoma suggesting sAxl as a biomarker of liver diseases. In this study we are the first to evaluate sAxl in human serum in comparison to Enhanced Liver Fibrosis (ELF) test and...

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Vydáno v:Cell Death Dis
Hlavní autoři: Staufer, Katharina, Dengler, Mirko, Huber, Heidemarie, Marculescu, Rodrig, Stauber, Rudolf, Lackner, Carolin, Dienes, Hans-Peter, Kivaranovic, Danijel, Schachner, Christian, Zeitlinger, Markus, Wulkersdorfer, Beatrix, Rauch, Peter, Prager, Gerhard, Trauner, Michael, Mikulits, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680921/
https://ncbi.nlm.nih.gov/pubmed/29072690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.554
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