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DCZ3301, a novel cytotoxic agent, inhibits proliferation in diffuse large B-cell lymphoma via the STAT3 pathway

Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma in adults, characterized by a rapidly increasing painless mass. A novel compound, DCZ3301, was synthesized that exerted direct cytotoxicity against DLBCL cell lines. The effects of DCZ3301 on DLBCL cells in vitro and in vivo a...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Sun, Xi, Li, Bo, Xie, Bingqian, Xu, Zhijian, Chang, Gaomei, Tao, Yi, Zhang, Yong, Chang, Shuaikang, Wang, Yingcong, Yu, Dandan, Xie, Yongsheng, Li, Tingye, Wang, Houcai, Chen, Gege, Hu, Liangning, Hou, Jun, Zhang, Yiwen, Xiao, Wenqin, Gao, Lu, Shi, Jumei, Zhu, Weiliang
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680593/
https://ncbi.nlm.nih.gov/pubmed/29022919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.472
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