Nalaganje...
DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2
Purpose: The present study investigates the effect of DCZ0814 in multiple myeloma (MM) cells, and determines the molecular mechanism of its antitumor activity against MM. Methods: The effects of DCZ0814 were evaluated in vitro using human MM cell lines (ARP1 and OCI-MY5) and in vivo in a murine xeno...
Shranjeno v:
| izdano v: | Cancer Manag Res |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Dove
2019
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6549748/ https://ncbi.nlm.nih.gov/pubmed/31213901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S194202 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|