CD10(−)/ALDH(−) cells are the sole cisplatin-resistant component of a novel ovarian cancer stem cell hierarchy

It is long established that tumour-initiating cancer stem cells (CSCs) possess chemoresistant properties. However, little is known of the mechanisms involved, particularly with respect to the organisation of CSCs as stem-progenitor-differentiated cell hierarchies. Here we aimed to elucidate the rela...

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Publicado en:Cell Death Dis
Autores principales: Ffrench, Brendan, Gasch, Claudia, Hokamp, Karsten, Spillane, Cathy, Blackshields, Gordon, Mahgoub, Thamir Mahmoud, Bates, Mark, Kehoe, Louise, Mooney, Aoibhinn, Doyle, Ronan, Doyle, Brendan, O'Donnell, Dearbhaile, Gleeson, Noreen, Hennessy, Bryan T, Stordal, Britta, O'Riain, Ciaran, Lambkin, Helen, O'Toole, Sharon, O'Leary, John J, Gallagher, Michael F
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680566/
https://ncbi.nlm.nih.gov/pubmed/29048400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.379
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