CD10(−)/ALDH(−) cells are the sole cisplatin-resistant component of a novel ovarian cancer stem cell hierarchy

It is long established that tumour-initiating cancer stem cells (CSCs) possess chemoresistant properties. However, little is known of the mechanisms involved, particularly with respect to the organisation of CSCs as stem-progenitor-differentiated cell hierarchies. Here we aimed to elucidate the rela...

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Bibliografski detalji
Izdano u:Cell Death Dis
Glavni autori: Ffrench, Brendan, Gasch, Claudia, Hokamp, Karsten, Spillane, Cathy, Blackshields, Gordon, Mahgoub, Thamir Mahmoud, Bates, Mark, Kehoe, Louise, Mooney, Aoibhinn, Doyle, Ronan, Doyle, Brendan, O'Donnell, Dearbhaile, Gleeson, Noreen, Hennessy, Bryan T, Stordal, Britta, O'Riain, Ciaran, Lambkin, Helen, O'Toole, Sharon, O'Leary, John J, Gallagher, Michael F
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680566/
https://ncbi.nlm.nih.gov/pubmed/29048400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.379
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