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AIP limits neurotransmitter release by inhibiting calcium bursts from the ryanodine receptor

Pituitary tumors are frequently associated with mutations in the AIP gene and are sometimes associated with hypersecretion of growth hormone. It is unclear whether other factors besides an enlarged pituitary contribute to the hypersecretion. In a genetic screen for suppressors of reduced neurotransm...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chen, Bojun, Liu, Ping, Hujber, Edward J., Li, Yan, Jorgensen, Erik M., Wang, Zhao-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680226/
https://ncbi.nlm.nih.gov/pubmed/29123133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01704-z
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