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Levetiracetam Inhibits Both Ryanodine and IP3 Receptor Activated Calcium Induced Calcium Release in Hippocampal Neurons in Culture

Epilepsy affects approximately 1% of the population worldwide, and there is a pressing need to develop new anti-epileptic drugs (AEDs) and understand their mechanisms of action. Levetiracetam (LEV) is a novel AED and despite its increasingly widespread clinical use, its mechanism of action is as yet...

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Detalhes bibliográficos
Main Authors: Nagarkatti, Nisha, Deshpande, Laxmikant S., DeLorenzo, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847576/
https://ncbi.nlm.nih.gov/pubmed/18406528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.02.076
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