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Structural insight into TPX2-stimulated microtubule assembly
During mitosis and meiosis, microtubule (MT) assembly is locally upregulated by the chromatin-dependent Ran-GTP pathway. One of its key targets is the MT-associated spindle assembly factor TPX2. The molecular mechanism of how TPX2 stimulates MT assembly remains unknown because structural information...
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| Publicado en: | eLife |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679754/ https://ncbi.nlm.nih.gov/pubmed/29120325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30959 |
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