The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability

Microtubules are cytoskeletal polymers whose function depends on their property to switch between states of growth and shrinkage. Growing microtubules are thought to be stabilized by a GTP cap at their ends. The nature of this cap, however, is still poorly understood. End Binding proteins (EBs) recr...

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Bibliographic Details
Published in:eLife
Main Authors: Roostalu, Johanna, Thomas, Claire, Cade, Nicholas Ian, Kunzelmann, Simone, Taylor, Ian A, Surrey, Thomas
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2020
Subjects:
Biochemistry and Chemical Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018511/
https://ncbi.nlm.nih.gov/pubmed/32053491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51992
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