Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling

Toddler/Apela/Elabela is a conserved secreted peptide that regulates mesendoderm development during zebrafish gastrulation. Two non-exclusive models have been proposed to explain Toddler function. The ‘specification model’ postulates that Toddler signaling enhances Nodal signaling to properly specif...

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Pubblicato in:eLife
Autori principali: Norris, Megan L, Pauli, Andrea, Gagnon, James A, Lord, Nathan D, Rogers, Katherine W, Mosimann, Christian, Zon, Leonard I, Schier, Alexander F
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2017
Soggetti:
Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679751/
https://ncbi.nlm.nih.gov/pubmed/29117894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22626
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