Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway

Busulphan (Bu) is an alkylating agent used in the conditioning regimen prior to hematopoietic stem cell transplantation (HSCT). Bu is extensively metabolized in the liver via conjugations with glutathione to form the intermediate metabolite (sulfonium ion) which subsequently is degraded to tetrahydr...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: El-Serafi, Ibrahim, Terelius, Ylva, Abedi-Valugerdi, Manuchehr, Naughton, Seán, Saghafian, Maryam, Moshfegh, Ali, Mattsson, Jonas, Potácová, Zuzana, Hassan, Moustapha
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679629/
https://ncbi.nlm.nih.gov/pubmed/29121650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187294
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller