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Dengue virus NS1 cytokine-independent vascular leak is dependent on endothelial glycocalyx components

Dengue virus (DENV) is the most prevalent, medically important mosquito-borne virus. Disease ranges from uncomplicated dengue to life-threatening disease, characterized by endothelial dysfunction and vascular leakage. Previously, we demonstrated that DENV nonstructural protein 1 (NS1) induces endoth...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Glasner, Dustin R., Ratnasiri, Kalani, Puerta-Guardo, Henry, Espinosa, Diego A., Beatty, P. Robert, Harris, Eva
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679539/
https://ncbi.nlm.nih.gov/pubmed/29121099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006673
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