Magnitude and Functionality of the NS1-Specific Antibody Response Elicited by a Live-Attenuated Tetravalent Dengue Vaccine Candidate

BACKGROUND: Dengue virus (DENV) can cause life-threatening disease characterized by endothelial dysfunction and vascular leakage. DENV nonstructural protein 1 (NS1) induces human endothelial hyperpermeability and vascular leak in mice, and NS1 vaccination confers antibody-mediated protective immunit...

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Bibliographic Details
Published in:J Infect Dis
Main Authors: Sharma, Mayuri, Glasner, Dustin R, Watkins, Heather, Puerta-Guardo, Henry, Kassa, Yoseph, Egan, Michael A, Dean, Hansi, Harris, Eva
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7325620/
https://ncbi.nlm.nih.gov/pubmed/30783676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz081
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