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LOSS OF HYPERDIRECT PATHWAY CORTICO-SUBTHALAMIC INPUTS FOLLOWING DEGENERATION OF MIDBRAIN DOPAMINE NEURONS
The motor symptoms of Parkinson’s disease (PD) are linked to abnormally correlated and coherent activity in the cortex and subthalamic nucleus (STN). However, in parkinsonian mice we found that cortico-STN transmission strength had diminished by 50–75% through loss of axo-dendritic and axo-spinous s...
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| 發表在: | Neuron |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679443/ https://ncbi.nlm.nih.gov/pubmed/28910619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.08.038 |
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