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Early dysfunction and progressive degeneration of the subthalamic nucleus in mouse models of Huntington's disease
The subthalamic nucleus (STN) is an element of cortico-basal ganglia-thalamo-cortical circuitry critical for action suppression. In Huntington's disease (HD) action suppression is impaired, resembling the effects of STN lesioning or inactivation. To explore this potential linkage, the STN was s...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5199195/ https://ncbi.nlm.nih.gov/pubmed/27995895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21616 |
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