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Peripheral deletion of CD8 T cells requires p38 mitogen activated protein kinase in cross-presenting dendritic cells
Peripheral tolerance mechanisms exist to prevent autoimmune destruction by self-reactive T cells that escape thymic deletion. Dominant tolerance imposed by CD4+FoxP3+ T regulatory cells can actively control auto-aggressive T cell responses. Tolerance mechanisms that act endogenous to the T cell also...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679299/ https://ncbi.nlm.nih.gov/pubmed/28864471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700427 |
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