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Molecular mechanisms determining lifespan in short- and long-lived species

Aging is a global decline of physiological functions, leading to an increased susceptibility to diseases and ultimately death. Maximum lifespans differ up to 200-fold between mammalian species. Although considerable progress has been achieved in identifying conserved pathways that regulate individua...

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Bibliographic Details
Published in:Trends Endocrinol Metab
Main Authors: Tian, Xiao, Seluanov, Andrei, Gorbunova, Vera
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679293/
https://ncbi.nlm.nih.gov/pubmed/28888702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2017.07.004
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