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Mitochondrial Inverted Repeats Strongly Correlate with Lifespan: mtDNA Inversions and Aging

Mitochondrial defects are implicated in aging and in a multitude of age-related diseases, such as cancer, heart failure, Parkinson’s disease, and Huntington’s disease. However, it is still unclear how mitochondrial defects arise under normal physiological conditions. Mitochondrial DNA (mtDNA) deleti...

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Detalhes bibliográficos
Main Authors: Yang, Jiang-Nan, Seluanov, Andrei, Gorbunova, Vera
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775743/
https://ncbi.nlm.nih.gov/pubmed/24069185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073318
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