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Interspecies Chimerism with Mammalian Pluripotent Stem Cells
Interspecies blastocyst complementation enables organ-specific enrichment of xenogenic pluripotent stem cell (PSC) derivatives. Here, we establish a versatile blastocyst complementation platform based on CRISPR-Cas9-mediated zygote genome editing and show enrichment of rat PSC-derivatives in several...
Shranjeno v:
| izdano v: | Cell |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679265/ https://ncbi.nlm.nih.gov/pubmed/28129541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.12.036 |
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