Interspecies Chimerism with Mammalian Pluripotent Stem Cells

Interspecies blastocyst complementation enables organ-specific enrichment of xenogenic pluripotent stem cell (PSC) derivatives. Here, we establish a versatile blastocyst complementation platform based on CRISPR-Cas9-mediated zygote genome editing and show enrichment of rat PSC-derivatives in several...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Wu, Jun, Platero-Luengo, Aida, Sakurai, Masahiro, Sugawara, Atsushi, Gil, Maria Antonia, Yamauchi, Takayoshi, Suzuki, Keiichiro, Bogliotti, Yanina Soledad, Cuello, Cristina, Valencia, Mariana Morales, Okumura, Daiji, Luo, Jingping, Vilariño, Marcela, Parrilla, Inmaculada, Soto, Delia Alba, Martinez, Cristina A., Hishida, Tomoaki, Sánchez-Bautista, Sonia, Martinez-Martinez, M. Llanos, Wang, Huili, Nohalez, Alicia, Aizawa, Emi, Martinez-Redondo, Paloma, Ocampo, Alejandro, Reddy, Pradeep, Roca, Jordi, Maga, Elizabeth A., Esteban, Concepcion Rodriguez, Berggren, W. Travis, Delicado, Estrella Nuñez, Lajara, Jeronimo, Guillen, Isabel, Guillen, Pedro, Campistol, Josep M., Martinez, Emilio A., Ross, Pablo Juan, Belmonte, Juan Carlos Izpisua
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679265/
https://ncbi.nlm.nih.gov/pubmed/28129541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.12.036
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