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B cell–derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity
Recent studies have identified critical roles for B cells in triggering autoimmune germinal centers (GCs) in systemic lupus erythematosus (SLE) and other disorders. The mechanisms whereby B cells facilitate loss of T cell tolerance, however, remain incompletely defined. Activated B cells produce int...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5679179/ https://ncbi.nlm.nih.gov/pubmed/28899868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170580 |
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