The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes

Myocardial infarction (MI) elicits massive inflammatory leukocyte recruitment to the heart. Here, we hypothesized that excessive leukocyte invasion leads to heart failure and death during acute myocardial ischemia. We found that shortly and transiently after onset of ischemia, human and mouse cardia...

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Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Anzai, Atsushi, Choi, Jennifer L., He, Shun, Fenn, Ashley M., Nairz, Manfred, Rattik, Sara, McAlpine, Cameron S., Mindur, John E., Chan, Christopher T., Iwamoto, Yoshiko, Tricot, Benoit, Wojtkiewicz, Gregory R., Weissleder, Ralph, Libby, Peter, Nahrendorf, Matthias, Stone, James R., Becher, Burkhard, Swirski, Filip K.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679174/
https://ncbi.nlm.nih.gov/pubmed/28978634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170689
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