The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes

Myocardial infarction (MI) elicits massive inflammatory leukocyte recruitment to the heart. Here, we hypothesized that excessive leukocyte invasion leads to heart failure and death during acute myocardial ischemia. We found that shortly and transiently after onset of ischemia, human and mouse cardia...

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Bibliographic Details
Published in:J Exp Med
Main Authors: Anzai, Atsushi, Choi, Jennifer L., He, Shun, Fenn, Ashley M., Nairz, Manfred, Rattik, Sara, McAlpine, Cameron S., Mindur, John E., Chan, Christopher T., Iwamoto, Yoshiko, Tricot, Benoit, Wojtkiewicz, Gregory R., Weissleder, Ralph, Libby, Peter, Nahrendorf, Matthias, Stone, James R., Becher, Burkhard, Swirski, Filip K.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2017
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679174/
https://ncbi.nlm.nih.gov/pubmed/28978634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170689
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