Lp-PLA(2) Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages

Healing after myocardial infarction (MI) involves the biphasic accumulation of inflammatory Ly-6C(high) and reparative Ly-6C(low) monocytes/macrophages. Excessive inflammation disrupts the balance between the 2 phases, impairs infarct healing, and contributes to left ventricle remodeling and heart f...

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Pubblicato in:Circ Heart Fail
Autori principali: He, Shun, Chousterman, Benjamin G., Fenn, Ashley, Anzai, Atsushi, Nairz, Manfred, Brandt, Martin, Hilgendorf, Ingo, Sun, Yuan, Ye, Yu-Xiang, Iwamoto, Yoshiko, Tricot, Benoit, Weissleder, Ralph, Macphee, Colin, Libby, Peter, Nahrendorf, Matthias, Swirski, Filip K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2015
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568849/
https://ncbi.nlm.nih.gov/pubmed/26232205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.115.002334
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