RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense

Many pathogens deliver virulence factors or effectors into host cells in order to evade host defenses and establish infection. Although such effector proteins disrupt critical cellular signaling pathways, they also trigger specific antipathogen responses, a process termed “effector-triggered immunit...

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Bibliographic Details
Published in:J Exp Med
Main Authors: Peterson, Lance W., Philip, Naomi H., DeLaney, Alexandra, Wynosky-Dolfi, Meghan A., Asklof, Kendra, Gray, Falon, Choa, Ruth, Bjanes, Elisabet, Buza, Elisabeth L., Hu, Baofeng, Dillon, Christopher P., Green, Douglas R., Berger, Scott B., Gough, Peter J., Bertin, John, Brodsky, Igor E.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2017
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679171/
https://ncbi.nlm.nih.gov/pubmed/28855241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170347
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