RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense

Many pathogens deliver virulence factors or effectors into host cells in order to evade host defenses and establish infection. Although such effector proteins disrupt critical cellular signaling pathways, they also trigger specific antipathogen responses, a process termed “effector-triggered immunit...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Med
Prif Awduron: Peterson, Lance W., Philip, Naomi H., DeLaney, Alexandra, Wynosky-Dolfi, Meghan A., Asklof, Kendra, Gray, Falon, Choa, Ruth, Bjanes, Elisabet, Buza, Elisabeth L., Hu, Baofeng, Dillon, Christopher P., Green, Douglas R., Berger, Scott B., Gough, Peter J., Bertin, John, Brodsky, Igor E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2017
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679171/
https://ncbi.nlm.nih.gov/pubmed/28855241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170347
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