RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense

Many pathogens deliver virulence factors or effectors into host cells in order to evade host defenses and establish infection. Although such effector proteins disrupt critical cellular signaling pathways, they also trigger specific antipathogen responses, a process termed “effector-triggered immunit...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Peterson, Lance W., Philip, Naomi H., DeLaney, Alexandra, Wynosky-Dolfi, Meghan A., Asklof, Kendra, Gray, Falon, Choa, Ruth, Bjanes, Elisabet, Buza, Elisabeth L., Hu, Baofeng, Dillon, Christopher P., Green, Douglas R., Berger, Scott B., Gough, Peter J., Bertin, John, Brodsky, Igor E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5679171/
https://ncbi.nlm.nih.gov/pubmed/28855241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170347
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