Comparative analysis of the GNAQ, GNA11, SF3B1, and EIF1AX driver mutations in melanoma and across the cancer spectrum

Uveal melanoma is characterized by recurrent mutations in GNAQ, GNA11, SF3B1, and EIF1AX, as well as a low total mutational burden. The frequency and clinical significance of these mutations in non-uveal melanoma and other cancers is not well described. We identified that GNAQ/GNA11 mutations occur...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Pigment Cell Melanoma Res
Hauptverfasser: Johnson, Douglas B., Roszik, Jason, Shoushtari, Alexander N., Eroglu, Zeynep, Balko, Justin, Higham, Catherine, Puzanov, Igor, Patel, Sapna P., Sosman, Jeffrey A., Woodman, Scott E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678944/
https://ncbi.nlm.nih.gov/pubmed/27089234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12482
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge