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Detection of mutations in SF3B1, EIF1AX and GNAQ in primary orbital melanoma by candidate gene analysis

BACKGROUND: Ocular melanoma is a rare but often deadly malignancy that arises in the uvea (commonest primary site), conjunctiva or the orbit. Primary orbital melanoma (POM) is exceedingly rare, with approximately 60 cases reported to date. Despite recent advances in our understanding of the genetics...

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發表在:BMC Cancer
Main Authors: Rose, Anna M., Luo, Rong, Radia, Utsav K., Kalirai, Helen, Thornton, Sophie, Luthert, Philip J., Jayasena, Channa N., Verity, David H., Coupland, Sarah E., Rose, Geoffrey E.
格式: Artigo
語言:Inglês
出版: BioMed Central 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6297940/
https://ncbi.nlm.nih.gov/pubmed/30558566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5190-z
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