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Dynamic Architecture of the Purinosome Involved in Human De Novo Purine Biosynthesis

Enzymes in human de novo purine biosynthesis have been demonstrated to form a reversible, transient multienzyme complex, the purinosome, upon purine starvation. However, characterization of purinosomes has been limited to HeLa cells and has heavily relied on qualitative examination of their subcellu...

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Библиографические подробности
Опубликовано в: :Biochemistry
Главные авторы: Kyoung, Minjoung, Russell, Sarah J., Kohnhorst, Casey L., Esemoto, Nopondo N., An, Songon
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678927/
https://ncbi.nlm.nih.gov/pubmed/25540829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501480d
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