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Dynamic Architecture of the Purinosome Involved in Human De Novo Purine Biosynthesis
Enzymes in human de novo purine biosynthesis have been demonstrated to form a reversible, transient multienzyme complex, the purinosome, upon purine starvation. However, characterization of purinosomes has been limited to HeLa cells and has heavily relied on qualitative examination of their subcellu...
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| Udgivet i: | Biochemistry |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5678927/ https://ncbi.nlm.nih.gov/pubmed/25540829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501480d |
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