Human single chain-transbodies that bound to domain-I of non-structural protein 5A (NS5A) of hepatitis C virus

A safe and broadly effective direct acting anti-hepatitis C virus (HCV) agent that can withstand the viral mutation is needed. In this study, human single chain antibody variable fragments (HuscFvs) to conserved non-structural protein-5A (NS5A) of HCV were produced by phage display technology. Recom...

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發表在:Sci Rep
Main Authors: Glab-ampai, Kittirat, Chulanetra, Monrat, Malik, Aijaz Ahmad, Juntadech, Thanate, Thanongsaksrikul, Jeeraphong, Srimanote, Potjanee, Thueng-in, Kanyarat, Sookrung, Nitat, Tongtawe, Pongsri, Chaicumpa, Wanpen
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678119/
https://ncbi.nlm.nih.gov/pubmed/29118372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14886-9
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