Whole Genome Sequence Analysis of Mutations Accumulated in rad27Δ Yeast Strains with Defects in the Processing of Okazaki Fragments Indicates Template-Switching Events

Okazaki fragments that are formed during lagging strand DNA synthesis include an initiating primer consisting of both RNA and DNA. The RNA fragment must be removed before the fragments are joined. In Saccharomyces cerevisiae, a key player in this process is the structure-specific flap endonuclease,...

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Vydáno v:G3 (Bethesda)
Hlavní autoři: Omer, Sumita, Lavi, Bar, Mieczkowski, Piotr A., Covo, Shay, Hazkani-Covo, Einat
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2017
Témata:
Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677150/
https://ncbi.nlm.nih.gov/pubmed/28974572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.300262
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