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Numt-Mediated Double-Strand Break Repair Mitigates Deletions during Primate Genome Evolution

Non-homologous end joining (NHEJ) is the major mechanism of double-strand break repair (DSBR) in mammalian cells. NHEJ has traditionally been inferred from experimental systems involving induced double strand breaks (DSBs). Whether or not the spectrum of repair events observed in experimental NHEJ r...

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Bibliographische Detailangaben
Hauptverfasser: Hazkani-Covo, Einat, Covo, Shay
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567098/
https://ncbi.nlm.nih.gov/pubmed/18949041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000237
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