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Numt-Mediated Double-Strand Break Repair Mitigates Deletions during Primate Genome Evolution

Non-homologous end joining (NHEJ) is the major mechanism of double-strand break repair (DSBR) in mammalian cells. NHEJ has traditionally been inferred from experimental systems involving induced double strand breaks (DSBs). Whether or not the spectrum of repair events observed in experimental NHEJ r...

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Main Authors: Hazkani-Covo, Einat, Covo, Shay
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567098/
https://ncbi.nlm.nih.gov/pubmed/18949041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000237
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