Higher PD-1 expression concurrent with exhausted CD8+ T cells in patients with de novo acute myeloid leukemia

OBJECTIVE: To investigate the association between the T cell inhibitory receptor programmed death 1 (PD-1) and T cell exhaustion status in T cells from patients with de novo acute myeloid leukemia (AML) and AML in complete remission (CR). METHODS: Surface expression of PD-1 and the exhaustion and im...

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Veröffentlicht in:Chin J Cancer Res
Hauptverfasser: Tan, Jiaxiong, Chen, Shaohua, Lu, Yuhong, Yao, Danlin, Xu, Ling, Zhang, Yikai, Yang, Lijian, Chen, Jie, Lai, Jing, Yu, Zhi, Zhu, Kanger, Li, Yangqiu
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677131/
https://ncbi.nlm.nih.gov/pubmed/29142466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21147/j.issn.1000-9604.2017.05.11
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