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The effect of genetic variation on promoter usage and enhancer activity

The identification of genetic variants affecting gene expression, namely expression quantitative trait loci (eQTLs), has contributed to the understanding of mechanisms underlying human traits and diseases. The majority of these variants map in non-coding regulatory regions of the genome and their id...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Garieri, Marco, Delaneau, Olivier, Santoni, Federico, Fish, Richard J., Mull, David, Carninci, Piero, Dermitzakis, Emmanouil T., Antonarakis, Stylianos E., Fort, Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677018/
https://ncbi.nlm.nih.gov/pubmed/29116076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01467-7
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