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The effect of genetic variation on promoter usage and enhancer activity

The identification of genetic variants affecting gene expression, namely expression quantitative trait loci (eQTLs), has contributed to the understanding of mechanisms underlying human traits and diseases. The majority of these variants map in non-coding regulatory regions of the genome and their id...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Garieri, Marco, Delaneau, Olivier, Santoni, Federico, Fish, Richard J., Mull, David, Carninci, Piero, Dermitzakis, Emmanouil T., Antonarakis, Stylianos E., Fort, Alexandre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677018/
https://ncbi.nlm.nih.gov/pubmed/29116076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01467-7
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