Site-directed RNA repair of endogenous Mecp2 RNA in neurons

Rett syndrome (RTT) is a debilitating neurological disorder caused by mutations in the gene encoding the transcription factor Methyl CpG Binding Protein 2 (MECP2). A distinct disorder results from MECP2 gene duplication, suggesting that therapeutic approaches must restore close to normal levels of M...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Sinnamon, John R., Kim, Susan Y., Corson, Glen M., Song, Zhen, Nakai, Hiroyuki, Adelman, John P., Mandel, Gail
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676935/
https://ncbi.nlm.nih.gov/pubmed/29078406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715320114
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker