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Antiviral screening identifies adenosine analogs targeting the endogenous dsRNA Leishmania RNA virus 1 (LRV1) pathogenicity factor

The endogenous double-stranded RNA (dsRNA) virus Leishmaniavirus (LRV1) has been implicated as a pathogenicity factor for leishmaniasis in rodent models and human disease, and associated with drug-treatment failures in Leishmania braziliensis and Leishmania guyanensis infections. Thus, methods targe...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Kuhlmann, F. Matthew, Robinson, John I., Bluemling, Gregory R., Ronet, Catherine, Fasel, Nicolas, Beverley, Stephen M.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293060/
https://ncbi.nlm.nih.gov/pubmed/28096399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619114114
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