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Control of transcriptional activity by design of charge patterning in the intrinsically disordered RAM region of the Notch receptor
Intrinsically disordered regions (IDRs) play important roles in proteins that regulate gene expression. A prominent example is the intracellular domain of the Notch receptor (NICD), which regulates the transcription of Notch-responsive genes. The NICD sequence includes an intrinsically disordered RA...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5676888/ https://ncbi.nlm.nih.gov/pubmed/29078291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706083114 |
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