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Ion Mobility Mass Spectrometry Uncovers the Impact of the Patterning of Oppositely Charged Residues on the Conformational Distributions of Intrinsically Disordered Proteins

[Image: see text] The global dimensions and amplitudes of conformational fluctuations of intrinsically disordered proteins are governed, in part, by the linear segregation versus clustering of oppositely charged residues within the primary sequence. Ion mobility-mass spectrometry (IM-MS) affords uni...

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Bibliografski detalji
Izdano u:J Am Chem Soc
Glavni autori: Beveridge, Rebecca, Migas, Lukasz G., Das, Rahul K., Pappu, Rohit V., Kriwacki, Richard W., Barran, Perdita E.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2019
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488185/
https://ncbi.nlm.nih.gov/pubmed/30823702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b13483
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