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AQP3 is regulated by PPARγ and JNK in hepatic stellate cells carrying PNPLA3 I148M
Aquaglyceroporins (AQPs) allow the movement of glycerol that is required for triglyceride formation in hepatic stellate cells (HSC), as key cellular source of fibrogenesis in the liver. The genetic polymorphism I148M of the patatin-like phospholipase domain-containing 3 (PNPLA3) is associated with h...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5676689/ https://ncbi.nlm.nih.gov/pubmed/29116096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14557-9 |
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